What Is CBD? - Weed Magazine

Cannabidiol (CBD) is one of the naturally occurring cannabinoids discovered in cannabis plants.
Cannabidiol can be taken into the body in multiple ways, consisting of by inhalation of marijuana smoke or vapor, as an aerosol spray right into the cheek, and by mouth.
CBD oil is primarily sold as artisanal product in the form of a tincture, concentrate, capsule, topical, spray, or vape oil.
Even though it comes from marijuana plants, CBD doesn’t create a “high” effect or any form of intoxication — that’s caused by another cannabinoid, known as THC.

Is CBD Legal?

CBD is readily obtainable in most parts of the United States, though its exact legal status is in flux. All 50 states have laws legalizing CBD with varying degrees of restriction, and while the federal government still considers CBD in the same class as marijuana, it doesn’t habitually enforce against it.

CBD Health Benefits

So far, scientific research has found that CBD can help to treat two types of seizure disorders in children, when it’s in a medication (called Epidiolex) that’s been approved by the U.S. Food and Drug Administration.
Scientists are studying whether CBD might be effective in treating other conditions, including anxiety, sleep, pain, and drug and alcohol use disorders. For now, it’s too early to say. More research is underway to determine if CBD could be a promising treatment for these conditions.

CBD oil for bipolar disorder

Early reports show that taking cannabidiol does not improve manic episodes in people with bipolar disorders.

CBD oil for A type of inflammatory bowel disease (Crohn disease)

Early research shows that taking cannabidiol does not reduce disease activity in adults with Crohn disease.

CBD oil for Diabetes

Early research shows that taking cannabidiol does not improve blood glucose levels, blood insulin levels, or HbA1c in adults with type 2 diabetes.

CBD oil for dystonia

dystonia is a movement disorder marked by involuntary muscle contractions.
Early research suggests that taking cannabidiol daily for 6 weeks might improve dystonia by 20% to 50% in some people. Higher quality research is needed to confirm this.

CBD oil for fragile X syndrome

fragile- X syndrome is an inherited condition marked by learning disabilities.
Early research found that applying cannabidiol gel might reduce anxiety and improve behavior in patients with fragile X syndrome.

CBD oil for GVHD

GVHD or graft-versus-host disease is a condition in which a transplant attacks the body.
Graft-versus-host disease is a complication that can occur after a bone marrow transplant. In people with this condition, donor cells attack the person’s own cells. Early research shows that taking cannabidiol daily starting 7 days before bone marrow transplant and continuing for 30 days after transplant can extend the time it takes for a person to develop GVHD.

CBD oil for Huntington disease

Huntington disease is an inherited brain disorder that affects movements, emotions, and thinking.
Early research shows that taking cannabidiol daily does not improve symptoms of Huntington’s disease.

CBD oil for Insomnia

Insomnia is a sleep disorder in which you have trouble falling and/or staying asleep.
Early research suggests that taking 160 mg of cannabidiol before bed improves sleep time in people with insomnia. However, lower doses do not have this effect. Cannabidiol also does not seem to help people fall asleep and might reduce the ability to recall dreams.

CBD oil for Multiple sclerosis (MS)

Multiple sclerosis (MS) is a disease of the central nervous system that disrupts the flow of information within the brain, and between the brain and body.
There is inconsistent evidence on the effectiveness of cannabidiol for symptoms of multiple sclerosis. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness in people with MS. However, it does not appear to improve muscle spasms, tiredness, bladder control, the ability to move around, or well-being and quality of life.

CBD oil for withdrawal from heroin, morphine, and other opioid drugs

Early research shows that taking cannabidiol for 3 days reduces cravings and anxiety in people with heroin use disorder that are not using heroin or any other opioid drugs.

CBD oil for Parkinson disease

Parkinson’s disease is a progressive nervous system disorder that affects movement.
Some early research shows that taking cannabidiol daily for 4 weeks improves psychotic symptoms in people with Parkinson disease and psychosis.

CBD oil for Schizophrenia

Schizophrenia is a mental illness marked by significant changes in a person’s perceptions, thoughts, mood, and behavior.
Research on the use of cannabidiol for psychotic symptoms in people with schizophrenia is conflicting. Some early research suggests that taking cannabidiol four times daily for 4 weeks improves psychotic symptoms and might be as effective as the antipsychotic medication amisulpride. However, other early research suggests that taking cannabidiol for 14 days is not beneficial. The conflicting results might be related to the cannabidiol dose used and duration of treatment.

CBD oil for Quitting smoking

Early research suggests that inhaling cannabidiol with an inhaler for one week might reduce the number of cigarettes smoked by about 40% compared to baseline.

What CBD does to your brain and body?

Cannabidiol has effects on the brain. The exact cause for these effects is not clear. However, cannabidiol seems to prevent the breakdown of a chemical in the brain that affects pain, mood, and mental function. Preventing the breakdown of this chemical and increasing its levels in the blood seems to reduce psychotic symptoms associated with conditions such as schizophrenia. Cannabidiol might also block some of the psychoactive effects of delta-9-tetrahydrocannabinol (THC). Also, cannabidiol seems to reduce pain and anxiety.

Is it safe?

Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does.

cbd interactions with supplements

Cannabidiol can cause sleepiness or drowsiness. Using it along with other herbs and supplements that have the same effect might cause too much sleepiness. Some of these herbs and supplements include calamus, California poppy, catnip, hops, Jamaican dogwood, kava, L-tryptophan, melatonin, sage, SAMe, St. John’s wort, sassafras, skullcap, and others.

CBD Interactions With Other Drugs

Valproate: Valproic acid can cause liver injury. Taking cannabidiol with valproic acid might increase the chance of liver injury. Discontinuation or reduction in dosage of cannabidiol and/or valproic acid might be needed.
Clobazam (Onfi): Clobazam is changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down clobazam. This might increase the effects and side effects of clobazam.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include alprazolam (Xanax), amlodipine (Norvasc), clarithromycin (Biaxin), cyclosporine (Sandimmune), erythromycin, lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), verapamil (Calan, Isoptin) and many others.

Medications that decrease the breakdown of other medications in the liver (Cytochrome P450 3A4 (CYP3A4) inhibitors): Cannabidiol is broken down by the liver. Some medications might decrease how quickly the liver breaks down cannabidiol. Taking cannabidiol along with these medications might increase the effects and side effects of cannabidiol. Some medications that might decrease how quickly the liver breaks down cannabidiol include amiodarone (Cordarone), clarithromycin (Biaxin), diltiazem (Cardizem), erythromycin (E-mycin, Erythrocin), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Fortovase, Invirase), and many others.
Zonisamide: Zonisamide is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down zonisamide. This might increase levels of zonisamide in the body by a small amount.
Medications changed by the liver (Cytochrome P450 2C8 (CYP2C8) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include amiodarone (Cordarone), carbamazepine (Tegretol), chloroquine (Aralen), diclofenac (Voltaren), paclitaxel (Taxol), repaglinide (Prandin) and others.
Rufinamide (Banzel): Rufinamide is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down rufinamide. This might increase levels of rufinamide in the body by a small amount.
Eslicarbazepine (Aptiom): Eslicarbazepine is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down eslicarbazepine. This might increase levels of eslicarbazepine in the body by a small amount.
Sedative medications (CNS depressants): Cannabidiol might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking cannabidiol along with sedative medications might cause too much sleepiness. Some sedative medications include benzodiazepines, pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan), and others.
Medications that increase breakdown of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers): Cannabidiol is broken down by the liver. Some medications might increase how quickly the liver breaks down cannabidiol. Taking cannabidiol along with these medications might decrease the effects of cannabidiol. Some of these medicines include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.
Everolimus (Zostress): Everolimus is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down everolimus. This might increase levels of everolimus in the body.
Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include chlorzoxazone (Lorzone) and theophylline (Theo-Dur, others).
Medications that increase the breakdown of other medications by the liver (Cytochrome P450 2C19 (CYP2C19) inducers): Cannabidiol is broken down by the liver. Some medications might increase how quickly the liver breaks down cannabidiol. Taking cannabidiol along with these medications might decrease the effects of cannabidiol. Some medications that might increase the breakdown of cannabidiol in the liver include carbamazepine (Tegretol), prednisone (Deltasone), and rifampin (Rifadin, Rimactane).
Brivaracetam (Briviact): Brivaracetam is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down brivaracetam. This might increase levels of brivaracetam in the body.
Medications changed by the liver (Glucuronidated drugs): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. Taking cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of these medications. Some of these medications changed by the liver include acetaminophen (Tylenol, others) and oxazepam (Serax), haloperidol (Haldol), lamotrigine (Lamictal), morphine (MS Contin, Roxanol), zidovudine (AZT, Retrovir), and others.
Medications that decrease the breakdown of other medications by the liver (Cytochrome P450 2C19 (CYP2C19) inhibitors): Cannabidiol is broken down by the liver. Some medications might decrease how quickly the liver breaks down cannabidiol. Taking cannabidiol along with these medications might increase the effects and side effects of cannabidiol. Some medications that might decrease the breakdown cannabidiol in the liver include cimetidine (Tagamet), fluvoxamine (Luvox), omeprazole (Prilosec); ticlopidine (Ticlid), topiramate (Topamax), and others.
Medications changed by the liver (Cytochrome P450 3A5 (CYP3A5) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include testosterone, progesterone (Endometrin, Prometrium), nifedipine (Adalat CC, Procardia XL), cyclosporine (Sandimmune), and others.
Topiramate (Tompamax): Topiramate is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down topiramate. This might increase levels of topiramate in the body by a small amount.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, others), verapamil (Calan, Isoptin, others), and others.
Medications changed by the liver (Cytochrome P450 1B1 (CYP1B1) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include theophylline (Theo-Dur, others), omeprazole (Prilosec, Omesec), clozapine (Clozaril, FazaClo), progesterone (Prometrium, others), lansoprazole (Prevacid), flutamide (Eulexin), oxaliplatin (Eloxatin), erlotinib (Tarceva), and caffeine.
Medications changed by the liver (Cytochrome P450 2C19 (CYP2C19) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include proton pump inhibitors including omeprazole (Prilosec), lansoprazole (Prevacid), and pantoprazole (Protonix); diazepam (Valium); carisoprodol (Soma); nelfinavir (Viracept); and others.
Tacrolimus (Prograf): Tacrolimus is changed and broken down by the body. Cannabidiol might decrease how quickly the body breaks down tacrolimus. This might increase levels of tacrolimus in the body.
Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), and piroxicam (Feldene); celecoxib (Celebrex); amitriptyline (Elavil); warfarin (Coumadin); glipizide (Glucotrol); losartan (Cozaar); and others.
Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetine (Paxil), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), and others.
Medications changed by the liver (Cytochrome P450 2B6 (CYP2B6) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include ketamine (Ketalar), phenobarbital, orphenadrine (Norflex), secobarbital (Seconal), and dexamethasone (Decadron).
Medications changed by the liver (Cytochrome P450 2A6 (CYP2A6) substrates): Some medications are changed and broken down by the liver. Cannabidiol might decrease how quickly the liver breaks down some medications. In theory, using cannabidiol along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before using cannabidiol, talk to your healthcare provider if you take any medications that are changed by the liver. Some medications changed by the liver include nicotine, chlormethiazole (Heminevrin), coumarin, methoxyflurane (Penthrox), halothane (Fluothane), valproic acid (Depacon), disulfiram (Antabuse), and others.

CBD legal Status in European Countries

Is CBD legal in Albania?

No! CBD Is illegal in Albania.

Is CBD legal in Austria?

Yes, CBD products are legal to purchase in Austria with a prescription.

Is CBD legal in Belarus?

No! CBD Is illegal in Belarus.

Is CBD legal in Belgium?

Yes, CBD products are legal to purchase in Belgium with a prescription.

Is CBD legal in Bosnia and Herzegovina?

No! CBD Is illegal in Bosnia and Herzegovin.

Is CBD legal in Bulgaria?

Yes, CBD products are legal to purchase in Bulgaria.

Is CBD legal in Croatia?

Yes, CBD products are legal to purchase in Croatia.

Is CBD legal in Cyprus?

Yes, CBD products are legal to purchase in Cyprus.

Is CBD legal in Czechia / Czech Republic?

Yes, CBD products are legal to purchase in Czechia.

Is CBD legal in Denmark?

No! CBD Is illegal in Denmark.

Is CBD legal in Estonia?

Yes, CBD products are legal to purchase in Estonia.

Is CBD legal in Finland?

Yes, CBD products are legal to purchase in Finland.

Is CBD legal in France?

Yes, CBD products are legal to purchase in France. But only CBD with 0% THC are legal for sale and consumption in France.

Is CBD legal in Germany?

Yes, CBD products are legal to purchase in Germany with a prescription.

Is CBD legal in Greece?

Yes, CBD products are legal to purchase in Greece when concentration of THC does not exceed 0.2% at any point during production.

Is CBD legal in Hungary

Yes, CBD products are legal to purchase in Hungary if it produced from industrial hemp and the concentration of THC does not exceed 0.2% at any point during production.

Is CBD legal in Iceland?

No! CBD Is illegal in Iceland.

Is CBD legal in Ireland?

Yes, CBD products are legal to purchase in Ireland but only CBD extracted from cold-pressing is legal and the other that even the slightest trace of THC in CBD would make it illegal.

Is CBD legal in Italy?

Yes, CBD products are legal to purchase in Italy. But the content of THC throughout production is no more than 0.6%.

Is CBD legal in Latvia?

Yes, CBD products are legal to purchase in Latvia when the CBD source comes from industrial hemp and the concentration of THC does not exceed 0.2% during production.